How to know a pen drive has a virus: Having said autorun viruses are spreading on opening pen drive, how should I know there is a virus without even opening it?.ģ. Disable autorun of removal drives: First of all Windows autorun is the entry point for viruses to enter from USB drives, viruses modify autorun files, so we should turn off autorun on removable drives.Ģ. This post concentrates from basic user knowledge to intermediate on how to protect your computer from pen drive viruses and what to do when viruses infects pen drives.ġ. As there are advantages of using these, there are also some problems too, these are: auto run viruses and Trojans spreading through and infecting computer. USB drives are replacing CD/DVDs as people are preferring to use pen drives more often because of portability and maximum data storage possibility.